CLINICAL
APPLICATIONS & DISEASE - Multiple Sclerosis
Clinical
Applications & Disease > Multiple Sclerosis
Sine-wave Grating
Testing & Multiple Sclerosis :: Case
Study The chart below demonstrates the visual sensitivity between
eyes of a multiple sclerosis patient not found using Snellen acuity.
In this case, the sine-wave grating test detects a significant contrast
loss. *This patient has normal Snellen visual acuity.

"Unequivocal
results were obtained from the one control subject who had a (marginal)
medium frequency notch in the contrast sensitivity curve. This subject
had no appreciable difference in discrimination between left and right
eyes for the unfiltered broadband letter pair, suggesting that, at viewing
distances for which low cycle/width information fell into the notch,
he was able to use the remaining high cycle/width information for letter
discrimination, when it was available." (Quote,
in references, see: Regan D, et al. Contrast
sensitivity and Snellen acuity in multiple sclerosis. Figure,
in references, see: Ginsburg AP. Spatial
filtering and vision: implications for normal and abnormal vision.)
Clinical
Applications & Disease > Multiple Sclerosis